— Sungen
Softgel Technology
Improved Drug Absorption
Improved drug absorption is the primary reason for selection of Softgel as a dosage form.
Soft capsules are a single-unit solid dosage form, consisting of a liquid or semi-solid fill enveloped by a one piece sealed elastic outer shell.Advantages Of Softgel Technology
Increased Rate Of Absorption
The solution-softgel approach, the shell ruptures within minutes to release the drug solution in the GI fluid; it is usually the rate of absorption.
Inreased Bioavailibility Of Drug
The solution-softgel formulation provided around three times the bioavailability of saquinavir as measured by the area under the plasma-time curve (AUC), compared to a hard shell capsule formulation.
Decreased Variability Of Plasmatic Drug
High variability in drug plasma levels is a common characteristic of drugs with low bioavailability. So less variability, high bioavailibility.
Patient Compliance And Consumer Preference
Consumers expressed their preference for softgels in terms of ease of swallowing, absence of taste and convenience.
Safety For Potent And Cytotoxic Drugs
By preparing a solution or suspension of drug, where the active component is essentially protected from the environment by the liquid, such safety concerns and associated toxicities have been significantly reduced
Dose Uniformity Of Low Dose Drug And Product Stability
Liquid dosing has been realized to avoid the difficulties of poor powder flow and hence content uniformity Preparations of liquid-filled softgel have proven beneficial to oxidative or hydrolytic degradable drugs.
- Enhance The Bioavailability Of Your Poorly Water-soluble (Bcs Ii And Iv) Compounds
- Improve Dose Uniformity Of Your Potent Compounds And Minimize Patient-to-patient Variability
- Generate Faster Onset Of Action, Reducing Api Dose, Minimizing Side Effects, And Improving Your Overall Treatment Performance
- Reduce Development Time Through A Proven Dosage Form With A Strong Track Record Of Commercial Success
- Get Specialized Handling And Manufacturing For Your Hormones, Cytotoxics, Potent And Difficult Apis
- Differentiate Your Brand With Various Color, Shape, Size And Printing Options And Protect Your Product From Counterfeiting And Tampering
- Reconsider Your Product Life Cycle Management By Generating A Faster Onset Of Action, Reducing Api Dose, Minimizing Side Effects, And Improving Your Overall Treatment Performance.